Recombinant Human SDF-1 a（CXCL12） 貨號:300-28A 細胞因子
胞因子受體存在著可溶性形式，掌握可溶性細胞因子受體產(chǎn)生的規(guī)律及其生理和病理意義，必將擴展人們對細胞因子網(wǎng)絡(luò)作用的認識。檢測細胞因子及其受體的水平已成為基礎(chǔ)和臨床免疫學(xué)研究中的一個重要的方面。Catalog Number:
Catalog Number:
300-28A
Synonyms:
Stromal-Cell Derived Factor-1, CXCL12, PBSF
Description:
SDF-1α and β are stromal derived CXC chemokines, and signal through the CXCR4 receptor. SDF-1α and β chemoattract B and T cells, and have been shown to induce migration of CD34+ stem cells. Additionally, the SDF-1 proteins exert HIV suppressive activity in cells expressing the CXCR4 receptor. Recombinant human SDF-1α is an 8.0 kDa protein containing 68 amino acid residues.
AA Sequence:
KPVSLSYRCP CRFFESHVAR ANVKHLKILN TPNCALQIVA RLKNNNRQVC IDPKLKWIQE YLEKALNK
Source:
E.coli
Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Biological Activity:
Determined by its ability to chemoattract human peripheral T cells activated with PHA and IL-2 using a concentation of 20-80 ng/ml.
Cross Reactivity:
Mouse, Rat, Human, Bacteria, Leech, Hamster, Cow, Dog, Monkey
Research Interests:
 | AIDS / HIV |  | Chemotaxis |
 | Immune System |  | Inflammation |
 | Neurobiology |  | Stem Cells & Differentiation |
 | Wound Healing | ||
Country of Origin:
USA
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