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Corn oil (Synonyms: 玉米油)

參  考  價:550
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  • 型號

    HY-Y1888

  • 品牌

    MCE

  • 廠商性質(zhì)

    代理商

  • 所在地

    杭州市

規(guī)格

50ml 550元 10000瓶可售

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CAS號 8001-30-7 產(chǎn)地 國產(chǎn)
規(guī)格 50ml 級別 化工級
證書 ISO系列證書
Corn oil 是從玉米胚芽中提取出來的一種油,可作為藥物分子的載體。貨號:HY-Y1888

Corn oil  (Synonyms: 玉米油)

Corn oil 是從玉米胚芽中提取出來的一種油,可作為藥物分子的載體。

生物活性

Corn oil, extracted from the germ of corn, can be used as a carrier for drug molecules.


體內(nèi)研究(In Vivo)

Corn oil-gavaged rats have 54% lower serum growth hormone (GH) levels, and replacement of GH into corn oil-gavaged rats by osmotic minipump infusion increase in situ MNCL cell proliferation to rates observed in water-gavaged animals[1].

Corn oil is commonly used as a feed additive or a delivery vehicle for lipophilic substances In an animal research setting[3].
Corn oil can become contaminated and cause death/systemic infections several days after IP injections, so corn oil should be aliquoted and frozen (recommendation); thaw and make fresh solution each time.
Corn oil is more recommended for gavage administration[4].
Intraperitoneal oil application causes local inflammation with depletion of resident peritoneal macrophages[5].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:Female C57BL/6J mice (n = 90; age, 6 to 7 wk)[3]
Dosage:0.1 mL.
Administration:Intraperitoneal injection every 48 h for a total of 4 injections over a 7-d period.
Result:At day 21, pharmaceutical-grade (PG) corn oil had a significantly higher pathology score compared with nonpharmaceutical-grade corn oil. No other significant differences between the corn oil groups were observed. The use of nonpharmaceutical grade corn oil did not result in adverse clinical consequences and is presumed safe to use for intraperitoneal injection in mice.


性狀:Oil


CAS 號:8001-30-7


運輸條件

Room temperature in continental US; may vary elsewher


儲存方式

Pure form-20°C3 years

4°C2 years


參考文獻

  • [1]. Hursting SD, et al. Inhibition of rat mononuclear cell leukemia by corn oil gavage: in vivo, in situ and immune competence studies. Carcinogenesis. 1994 Feb;15(2):193-9.  [Content Brief]

    [2]. Gilbertson JR, et al. Inhibition of growth of Morris hepatomas 7777 and 7800 by corn oil. Oncology. 1977;34(2):62-4.  [Content Brief]

    [3]. Jennifer S Hubbard, et al. Effects of Repeated Intraperitoneal Injection of Pharmaceutical-grade and Nonpharmaceutical-grade Corn Oil in Female C57BL/6J Mice. J Am Assoc Lab Anim Sci. 2017 Nov 1;56(6):779-785.  [Content Brief]

    [4]. Administration Of Drugs and Experimental Compounds in Mice and Rats

    [5]. Elisenda Alsina-Sanchis, et al. Intraperitoneal Oil Application Causes Local Inflammation with Depletion of Resident Peritoneal Macrophages. Mol Cancer Res. 2021 Feb;19(2):288-300.  [Content Brief]

  • 注:產(chǎn)品僅用于科研


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